Fluctuating Serum Aspartate Aminotransferase Activity in a Complicated Pregnancy
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چکیده
منابع مشابه
Fluctuating serum aspartate aminotransferase activity in a complicated pregnancy.
A 29-year-old para 0 gravida 2 woman with a history of infertility and spontaneous abortion presented to her local hospital at 9 weeks gestation with severe nausea and vomiting. Symptoms persisted for 10 weeks, leading to the diagnosis of hyperemesis gravidarum and treatment with intravenous fluids (3 times/week) and Zofran. At 8 weeks gestation, laboratory tests were unremarkable with the exce...
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Elevated enzyme activities in plasma may at times be attributed to the presence of macro-enzymes. The macro-enzymes are often serum enzymes in complex with immunoglobulins, resulting in a greater molecular mass that cannot be filtered by renal glomeruli and are, hence, retained in the plasma. The aspartate aminotransferase (AST) can exist as a macro-enzyme, although it has been rarely reported....
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Effects of serum and protein on assays measuring aspartate aminotransferase (L-aspartate: 2-oxoglutarate aminotransferase, EC 2.6.1.1) were examined. Increasing amounts of normal human serum or human serum albumin in samples with fixed amounts of purified enzyme decrease absorbance values and thus distort the results obtained in an assay in which diazonium-salt chromogenic reagent is used. Seru...
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Azide at an effective antimicrobial concentration, 7.7 mmol/liter, inhibits neither the cytoplasmic or the mitochondrial isoenzymes of human aspartate aminotransferase (EC 2.6. 1. 1) or porcine malate dehydrogenase (EC 1.1.1.37). It markedly prolongs the usefulness of substrates in assays for estimating aspartate aminotransferase activity (aspartate substrate without azide deteriorates in less ...
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Aspartate aminotransfcrase (L-aspartate: 2-oxoglutarate aminotransferase, EC 2. 6.1.1) comprises two isoen&ymcs. One is anionic, is associated with the soluble fraction of the cell and ordinarily forms the bulk of the scrum activity. The other is cationic, and is associated with the mitochondria (1—7). Each may in turn be subdivisible (8—10), but it is unlikely that this will influence the pres...
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ژورنال
عنوان ژورنال: Clinical Chemistry
سال: 2015
ISSN: 0009-9147,1530-8561
DOI: 10.1373/clinchem.2014.228247